A simple and low-cost poly (dl-phenylalanine) modified carbon sensor for the improved electrochemical analysis of Riboflavin

Abstract

The current study reports on the electroanalysis of Riboflavin (RF) on the surface of a poly dl -phenylalanine modified carbon paste sensor (PDLPAMCPS). The developed sensor caused a noticeable electrocatalytic action for the redox activity of RF in a phosphate buffer solution (PBS) of pH 6.5. This analysis was evaluated using differential pulse voltammetry (DPV) and cyclic voltammetry (CV) techniques. The active surface of the functioning sensor exposes well developed anodic peak with prominent electron transfer. PDLPAMCPS shows distinctive and improved DPV and CV peaks for RF with and without the presence of organic dyes and dopamine (DA). The impact of the solution pH, scan rate, accumulation potential and concentration on RF at PDLPAMCPS were studied. A vibrant linear growth was observed between the oxidation peak current and the RF concentration in the range of 6.0 μM–30.0 μM, which provides a lower limit of detection (LOD) of 92 nM with excellent sensitivity. The proposed method and sensor were applied for the assessment of RF in medicine sample as an analytical application with fine recoveries and low LOD. • A simple and low-cost carbon sensor was designed using poly ( dl -Phenylalanine) for the sensing of Riboflavin. • Prepared sensor was characterized by CV, DPV, EIS and FE-SEM analysis. • Equipped sensor shows high sensitivity, selectivity and lower LOD of 92 nM towards Riboflavin detection. • Interference effect on prepared sensor for Riboflavin was studied.