Abstract

A diastereoselective (3+2) annulation of 4-isothiocyanato pyrazolones and 2-arylidene-indan-1,3-dione in the presence of 4-dimethylaminopyridine is explored. A wide range of novel dispiroheterocyclic products were achieved in high yield (up to 95 %) and excellent diastereoselectivity (up to >20:1 dr) via a simple sequential Michael addition/cyclization.

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.