Abstract

A short stereoselective synthesis of the acetoxy azetidinone (1), an important precursor of several biologically active β-lactam antibiotics, has been accomplished in seven steps and 32.8% overall yield from the easily available and inexpensive (R) ethyl 3-hydroxybutanoate. Chirality 10:91–94, 1998. © 1997 Wiley-Liss, Inc.

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