Abstract
In the 1960s, O'Sullivan and Mahan [1] firstly brought up the GDM diagnostic criteria by measuring the blood glucose levels in 752 pregnant women based on 3-hour 100 g oral glucose tolerance test (OGTT). They further validated the criteria by comparing future chances of developing Type 2 diabetes in mothers in a larger cohort (29% in abnormal OGTT vs. 17% in normal OGTT). It provided the evidence that the importance of detecting GDM during pregnancy. In 1979, the U.S. National Diabetes Data Group (NDDG) converted the blood glucose values proposed by O Sullivan to the equivalent values measured in plasma and recommended the following diagnostic criteria for GDM using 3-hour 100 g OGTT: a fasting plasma glucose ≥ 5.8 mmol/L (105 mg/dL); a 1-hour result of ≥ 10.6 mmol/L (190 mg/ dL); a 2-hour result of ≥ 9.2 mmol/L (165 mg/dL) and a 3-hour result of ≥ 8.1 mmol/L (145 mg/dL) [2].
Highlights
Gestational Diabetes Mellitus (GDM) is a common complication during pregnancy
In the 1960s, O'Sullivan and Mahan [1] firstly brought up the GDM diagnostic criteria by measuring the blood glucose levels in 752 pregnant women based on 3-hour 100 g oral glucose tolerance test (OGTT)
In 1979, the U.S National Diabetes Data Group (NDDG) converted the blood glucose values proposed by OSullivan to the equivalent values measured in plasma and recommended the following diagnostic criteria for GDM using 3-hour 100 g OGTT: a fasting plasma glucose ≥ 5.8 mmol/L (105 mg/dL); a 1-hour result of ≥ 10.6 mmol/L (190 mg/ dL); a 2-hour result of ≥ 9.2 mmol/L (165 mg/dL) and a 3-hour result of ≥ 8.1 mmol/L (145 mg/dL) [2]
Summary
Gestational Diabetes Mellitus (GDM) is a common complication during pregnancy. The initial diagnosis criteria were established almost 50 years ago and the debate on GDM diagnosis still persists in the global professional societies today. In the 1960s, O'Sullivan and Mahan [1] firstly brought up the GDM diagnostic criteria by measuring the blood glucose levels in 752 pregnant women based on 3-hour 100 g oral glucose tolerance test (OGTT). In 1979, the U.S National Diabetes Data Group (NDDG) converted the blood glucose values proposed by OSullivan to the equivalent values measured in plasma and recommended the following diagnostic criteria for GDM using 3-hour 100 g OGTT: a fasting plasma glucose ≥ 5.8 mmol/L (105 mg/dL); a 1-hour result of ≥ 10.6 mmol/L (190 mg/ dL); a 2-hour result of ≥ 9.2 mmol/L (165 mg/dL) and a 3-hour result of ≥ 8.1 mmol/L (145 mg/dL) [2].
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