Abstract
Among the 20 naturally occurring amino acids, alanine (Ala) has the highest helix propensity. Among noncoded -amino acids, -aminoisobutyric acid (Aib) is the helicogenic amino acid that has been used the most for designing helices, including those that have biological relevance. In order to establish the advantages and limitations of using Aib to design a peptide helix, that would otherwise be comprised of naturally occurring amino acids like Ala, it is important that a comparative analysis of release of the other resource required for this defense is triggered by the host upon contact with the pathogen. This newmechanism stands as a unique signal/response reaction and strikingly demonstrates how independent principles have developed for signal reception and response in marine algae.
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