Abstract
A sensor of the Unfolded Protein Response to study the stress induced in Yarrowia lipolytica strains by the production of heterologous proteins
Highlights
A critical step in the production of heterologous proteins in yeasts seems to be the efficiency of protein folding and assembly in the endoplasmic reticulum (ER)
In order to analyse the unfolded protein response (UPR) in the non-conventional yeast Yarrowia lipolytica, especially in relation with the production of heterologous proteins, we designed an UPR-sensor carried on an integrative vector
This sensor comprises the promoter from KAR2 gene directing the expression of the lacZ reporter gene
Summary
A sensor of the Unfolded Protein Response to study the stress induced in Yarrowia lipolytica strains by the production of heterologous proteins. Address: UMR1238 Microbiologie et Génétique Moléculaire, INRA/CNRS/INA-PG, CBAI, 78850 Thiverval-Grignon, France * Corresponding author from The 4th Recombinant Protein Production Meeting: a comparative view on host physiology Barcelona, Spain. Published: 10 October 2006 Microbial Cell Factories 2006, 5(Suppl 1):P5 doi:10.1186/1475-2859-5-S1-P5. The 4th Recombinant Protein Production Meeting: a comparative view on host physiology The organisers would like to thank Novozymes Delta Ltd who generously supported the meeting. Meeting abstracts – A single PDF containing all abstracts in this supplement is available here. http://www.biomedcentral.com/content/pdf/1475-2859-5-S1-info.pdf
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
