Abstract
This paper describes the design of an integrated sensor interface for neurochemical signal acquisition. Neurochemicals undergo oxidation and reduction reactions in the presence of an action potential. Thus, knowledge of the oxidation and reduction potentials of neurochemicals is important in the neurostimulation treatment of neurological and neurodegenerative diseases. The sensor interface circuit utilizes a mixed-signal design to detect the induced current from the neurochemical, in response to an applied voltage. The circuit is fabricated in 65nm CMOS technology and supports a wide input current range of ±1.2µA with a current resolution of 85.4pA, enabling detection of neurochemicals within the supported current range. Measured results with dopamine concentration of 500nMol demonstrate the ability of the sensor interface circuit to detect oxidation and reduction current peaks, indicating the release times and the required oxidation and reduction potentials for neurostimulation of the neurochemical.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.