Abstract

A sensitive colorimetric biosensor based on intermolecular split G-quadruplex DNAzymes and magnetic nanoparticles for the detection of Hg2+

Highlights

  • The mercury ion (Hg2+) is one of the most well-known widespread environmental pollutants and has distinct toxicological profiles that can cause deleterious effects on human health and the environment, even at low concentrations, as well as posing a challenge to the global plan of maintaining a sustainable environment[1,2]

  • Hemin is thegood catalyzer, the free form of hemin would be eliminated by washing step; a lower catalytic curve has been observed

  • magnetic nanoparticles (MNPs)-SA4 showed inherently low catalytic activities, and ABTS cannot be oxidised by hydrogen peroxide under the usual conditions

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Summary

Introduction

The mercury ion (Hg2+) is one of the most well-known widespread environmental pollutants and has distinct toxicological profiles that can cause deleterious effects on human health and the environment, even at low concentrations, as well as posing a challenge to the global plan of maintaining a sustainable environment[1,2]. We proposed a new colorimetric biosensor based on intermolecular split G-quadruplex DNAzymes for the detection of mercury ions.

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