Abstract
A selective and sensitive method to detect glutathione (GSH) based on the complex of a coumarin-based probe and Cu2+ is reported. In response to GSH, the system provides remarkable fluorescence intensity change with the color change from colorless to yellow, and the detect limit is determined to be 3.6×10−7M. The background amino acids show small or no interference on the detection of GSH. Moreover, this probe could be applied to detect GSH via intracellular fluorescent imaging.
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