Abstract
The improper management of wound exudate around the diabetic wound bed is one of the major factors leading to delay diabetic wound healing. However, the limited water absorption of single-layer conventional dressings unavoidably maintains excessive exudate in the diabetic wound bed. Herein, a novel diabetic wound dressing is reported for achieving rapid wound healing by electrospinning hydrophobic nanofibers on a hydrophilic modified non-woven fabric. The double-layer structure of the self-pumping dressing possesses unidirectional fluid transportation to divert excessive exudate away from diabetic wounds, ultimately promoting wound healing. The hydrophilic modified non-woven fabric provides water absorption and moisture retention to absorb excess exudate passing through the hydrophobic nanofiber, thereby preventing the wound bed from rewetting. Moreover, the formation of depressions on the hydrophobic nanofiber surfaces serves as water channels to further drain wound exudate from the wound bed. In vivo wound studies confirm that the self-pumping dressing exhibits excellent unidirectional wound exudate delivery and wound moisturization. Thus, diabetic wound healing shows a low inflammatory response and excellent wound healing quality. This self-pumping dressing exhibits clinical significance to design and fabricate a next-generation dressing for diabetic wound healing.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.