Highlights

  • Silicone-based pressure sensitive adhesives (PSA) are widely used as adhesives to wounded skin as they adhere with small applied pressure and after short contact time

  • We investigated the adhesive performance of self-adhesive elastomeric films for sensitive adhesion to tissue

  • The results show that the soft skin adhesive (SSA)-based films can be functionalized by physical protein adsorption with only a slight impact on the adhesive performance analyzed by tack tests and peel tests using two different substrates

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Summary

Introduction

Silicone-based pressure sensitive adhesives (PSA) are widely used as adhesives to wounded skin as they adhere with small applied pressure and after short contact time. Silicones are a versatile class of polymeric materials exhibiting a low surface free energy and high flexibility [4]. One of the most extensively used silicone elastomers is poly-(dimethylsiloxane) (PDMS) with broad application as a skin adhesive [1,5,6,7,8]. A subclass of PDMS, so called soft skin adhesives (SSAs), has been introduced, in particular for gentle skin applications. SSAs have the ability to adhere to rough surfaces including wet skin, exhibit a high water vapor permeability, and good compatibility with pharmaceutical compounds [7,8,9,10]. Cell-material interactions can be improved, e.g., by physical adsorption of proteins or oxygen plasma treatment [11,12,13,14]. Physical protein adsorption is primarily based on Polymers 2019, 11, 942; doi:10.3390/polym11060942 www.mdpi.com/journal/polymers

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