Abstract
Randomized clinical trials now provide compelling evidence supporting extracorporeal membrane oxygenation-facilitated cardiopulmonary resuscitation (ECPR) for highly selected patients with refractory out-of-hospital cardiac arrest (specifically, initially shockable rhythms, witnessed arrests, and presumed cardiac etiology). ECPR should be considered in centres with experienced ECMO teams. High-performing systems-of-care and institutional commitment are required to implement this logistically and technically complex therapy.
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