Abstract

The present study aims to: a) systematically map the of birth cohort studies from the South Asian region b) examine the major research foci and landmark contributions from these cohorts using reproducible scientometric techniques and c) offer recommendations on establishing new birth cohorts in Pakistan, building upon the strengths, weaknesses and gaps of previous cohorts. Bibliographic records for a total of 260 articles, published during through December 2018, were retrieved from the Web of Science (core database). All data were analysed using Microsoft Excel (2013), Web of Science platform and CiteSpace. A series of network analysis were then run for each time-period using the link reduction method and pathfinder network scaling. The co-cited articles were clustered into their homogeneous research clusters. The clusters were named using the Latent Semantic Indexing (LSI) method that utilized author keywords as source of names for these clusters. The scientometric analyses of original research output from these birth cohorts also paint a pessimistic landscape in Pakistan- where Pakistani sites for birth cohorts contributed only 31 publications; a majority of these utilized the MAL-ED birth cohort data. A majority of original studies were published from birth cohorts in India (156), Bangladesh (63), and Nepal (15). Out of these contributions, 31 studies reported data from multiple countries. The three major birth cohorts include prospective and multi-country MAL-ED birth cohort and The Pakistan Early Childhood Development Scale Up Trial, and a retrospective Maternal and infant nutrition intervention cohort. In addition to these, a few small-scale birth cohorts reported findings pertaining to neonatal sepsis, intrauterine growth retardation and its effects on linear growth of children and environmental enteropathy.

Highlights

  • The scientometric analyses of original research output from these birth cohorts paint a pessimistic landscape in Pakistan- where Pakistani sites for birth cohorts contributed only 31 publications, where a majority of these utilized the MAL-ED birth cohort data

  • Most original studies were published from birth cohorts in India (n = 156), Bangladesh (n = 63), and Nepal (n = 15)

  • The Mysore Pathenon Cohort and the MAASTHI cohorts in India have contributed to our understanding of gestational diabetes and insulin sensitivity and their intergenerational effects such as adiposity in offspring [4,40]

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Summary

Introduction

Birth cohorts in South Asia the University of Bristol and UK Medical Research Council (MC_UU_00011/6). The views expressed in this publication are those of the authors and not necessarily any funding bodies. The specific roles of these authors are articulated in the ‘author contributions’ section. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript

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