A SCARLATINIFORM RASH FROM ATOPHAN

Abstract

The patient, a woman aged 38, was admitted to the Medical Service of Roosevelt Hospital May 30, 1913, suffering from an acute polyarthritis involving knees, ankles, wrists, cervical spine, the temporomaxillary and many interphalangeal joints. The maximum temperature was 103. There was no history of previous attacks nor was there any cardiac involvement. Drug treatment was begun with large doses of sodium salicylate, 240 grains being given each twenty-four hours, from May 30 to June 4. The temperature fell to 101, but pain was not relieved. June 4 the sodium salicylate was discontinued and atophan 15 grains given three times a day to June 7, when the same dose was given every four hours. This was continued until June 11, when the dose was made 7½ grains every four hours. Pain was relieved and the tempera ture fell to 99. June 13 there was a sudden rise of temperature to