Abstract
A group of cells that can become adipocytes controls the formation of blood vessels in the bone marrow, and also regulates the differentiation of resident mesenchymal progenitor cells.
Highlights
Related research article Zhong L, Yao L, Tower RJ, Wei Y, Miao Z, Park J, Shrestha R, Wang L, Yu W, Holdreith N, Huang X, Zhang Y, Tong W, Gong Y, Ahn J, Susztak K, Dyment N, Li M, Long F, Chen C, Seale P, Qin L. 2020
Bone cells are derived from so-called bone marrow stromal cells (BMSCs), which are usually found near blood vessels
Older bones have an increased amount of fat in their marrow, and a large number of BMSCs express the receptor for leptin, a hormone that is often found in fat cells (Zhou et al, 2014)
Summary
Related research article Zhong L, Yao L, Tower RJ, Wei Y, Miao Z, Park J, Shrestha R, Wang L, Yu W, Holdreith N, Huang X, Zhang Y, Tong W, Gong Y, Ahn J, Susztak K, Dyment N, Li M, Long F, Chen C, Seale P, Qin L. 2020. F orget your prejudices against adipocytes – fat cells have important roles to play in the body. Bone cells are derived from so-called bone marrow stromal cells (BMSCs), which are usually found near blood vessels. Older bones have an increased amount of fat in their marrow, and a large number of BMSCs express the receptor for leptin, a hormone that is often found in fat cells (Zhou et al, 2014).
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