Abstract
Photochemistry Photochemistry offers an efficient route to constructing four-membered carbon rings, but the product geometry is hard to control precisely. Even though catalysts can selectively orient the reacting partners, it is hard to outpace the unselective background reaction stimulated by catalyst-free light absorption. Huang et al. devised a chiral rhodium catalyst that enhanced the intrinsic blue light absorption of imidazole-substituted enones by more than 100-fold, thereby accelerating their [2+2] reaction with dienes and styrene derivatives. The acceleration was sufficient to achieve 92 to 99% enantiomeric excess in a wide variety of cyclobutane products, several of which bore contiguous quaternary stereocenters. J. Am. Chem. Soc. 10.1021/jacs.7b04363 (2017).
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
