A Review on the use of Midazolam as a Co-induction Agent

Abstract

The practice of delivering a small amount of sedative or another anesthetic drug to lessen the dose of induction agent necessary has been known as co-induction. In other terms, employment of two or more medications to generate anaesthesia is referred to as co-induction of anaesthesia [1,2]. As a coinduction agent, various medications have been trailed out. We'll look at the drug midazolam, its pharmacology, and how successful it is as a coinduction agent in this article. Midazolam has been proven to minimize the amount of propofol required to produce anaesthesia by up to 50% without compromising the recovery profile when administered in this fashion [3,4]. We looked at the literature on the drug midazolam and coinduction agents that was available on different platforms such as PubMed, medline, Scopus, Web of Science, and Google Scholar. We looked at several articles about midazolam and coinduction agents, as well as articles where midazolam was utilized as a coinduction agent. Prior observational studies and case reports using midazolam as a coinduction agent were mentioned in this article. After studying about midazolam's pharmacology, usage, indications, contraindications, as well as past observational studies and case reports, The substance can be used as a coinduction agent and has a variety of purposes in anaesthesia.