Abstract
ABSTRACT 
 Basti Karma is the most widely used and highly effective treatment modality in Panchakarma. Though Basti is specially indicated for Vatika diseases but it is mentioned in vitiation of all the Vata, Pitta, Kapha, Rakta Doshika disorders. Correctly given Basti will stay in the Pakawashaya, Shroni, Nabhi and Adhobhaga. Basti Dravya will reach the entire Srotasa, in view of its Veerya and produces alleviating action Shamanadi karmas. References regarding Basti Karmuktwa were collected from various classical and Ayurveda published works, published research papers from Pub Med, Google Scholar and compilation was done. Concept of Pharmacodynamics of Basti was studied in detail. Basti is most often recommended practice in Vata Roga Chikitsa. Most of the previous studies have emphasized on the importance of Basti in Vata vyadhis; however there were limited studies carried out on pharmacodynamics of Basti only. Pharmacodynamics outcome of Basti Karma may be due to functioning of the one or more effect of different mechanism.
 
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