Abstract

Due to variety of pediatric population and barriers of modern technologies it looks that a single formulation strategy will now not be suited for all pediatric patients. The determination of a suitable formulation strategy for a targeted population crew wants to be cautiously considered for every individual product. When managing patients who can't swallow solid oral dosage forms, switching to choice liquid components or different route is greater suitable. To limit unnecessary drugs manipulation it is fundamental for prescribers to think about age appropriateness, type of formulation (in relation to ease of administration), swallowing issues and patient capability to swallow. Palatability needs to be considered carefully by pharmaceutical companies when designing new formulations and also by prescribers in order to optimize effective prescribing, adherence, therapeutic results and lowering wastage with cost savings. . Majority of drugs prescribed for children have not been competently examined in pediatric population. Future formulation work needs to be carried out to strengthen pediatric based formulations. Formulations accepted by children need to be accessible in suitable unit doses covering child dosing ranges and it should be able to tapered accordingly. Monolithic solid dosage form was discovered to be an alternative choice in case of unavailable liquid dosage form. It is very necessary therefore that all requests to crush, split, or opening of capsules have to be discussed with clinical pharmacist prior to beginning administration of the crushed products.

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