Abstract
A review on SNP and other types of molecular markers and their use in animal genetics
Highlights
INTRODUCTIONMolecular markers, revealing polymorphisms at the DNA level, are key players in animal genetics
OLDER TYPES OF MOLECULAR GENETIC MARKERSMolecular markers, revealing polymorphisms at the DNA level, are key players in animal genetics
If we consider molecular genetic DNA markers in terms of the type of information they provide at a single locus, only three main categories can be described, in increasing degrees of interest: the bi-allelic dominant, such as RAPDs, AFLPs; the bi-allelic co-dominant, such as RFLPs, Single strand conformation polymorphism (SSCP) and the multi-allelic co-dominant, such as the microsatellites
Summary
Molecular markers, revealing polymorphisms at the DNA level, are key players in animal genetics. If we consider molecular genetic DNA markers in terms of the type of information they provide at a single locus, only three main categories can be described, in increasing degrees of interest: the bi-allelic dominant, such as RAPDs (random amplification of polymorphic DNA), AFLPs (amplified fragment length polymorphism); the bi-allelic co-dominant, such as RFLPs (restriction fragment length polymorphism), SSCPs (single stranded conformation polymorphism) and the multi-allelic co-dominant, such as the microsatellites. Bearing this in mind, some variations in the popularity of the markers used at different periods of time in the recent and quickly evolving field of molecular genetics, can be understood. Comparisons with other types of markers will be done, as a guideline to the markers to be chosen according to the various types of studies envisaged
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
