A REVIEW ON SESBANIA GRANDIFLORA ITS EFFECT ON THE TREATMENT OF DEMENTIA AND NEURO DISEASE AND OTHER DISEASES

Abstract

One of the most often used folk medicines is Sesbania grandiflora, better known as the Agati or Hummingbird tree. Anemia, bacterial infections, TB, and other illnesses can be treated with the plant's pharmacological properties. Agati's anticancer and hepatoprotective properties are attributable to the presence of phytochemical ingredients. Sesbania grandiflora's therapeutic characteristics are the topic of this article. Normal psychological functioning and behavioural patterns are disrupted by dementia. One to four percent of the world's population over the age of 65 is affected by dementia, which is a neurological disease. Dementia is caused by a number of different factors. Because dementia is more common in those who have cardiovascular and neurodegenerative conditions (such hypertension, hypercholesterolemia, diabetes and cerebral ischemia), these people are more likely to develop it. In addition to alcohol and tobacco use, these conditions are exacerbated. Alzheimer's dementia, vascular dementia, frontotemporal dementia, semantic dementia, and dementia with Lewy bodies are the most frequent kinds of dementia. As we get older, Alzheimer's and Lewy body dementias become more common. It is the second most frequent kind of dementia after Alzheimer's disease (AD), and it can be caused by long-term cardiovascular disease (CVD). Deterioration in semantic memory is a hallmark of semantic dementia (knowledge of objects, people, concepts and words). synuclein aggregation in Lewy body dementia (LBD) impairs neuronal growth and has a significant impact on the disease aetiology. Alzheimer's disease, Parkinson's disease, schizophrenia, and other neurodegenerative diseases all have a strong genetic component, as do frontotemporal dementia and Alzheimer's disease. An important part of this study is the discussion of the role of glutathione (GSH), SOD, GPx, and Catalase (Cat) during oxidative stress and the link between mitochondrial dysfunction and many disorders, including dementia. The purpose of this review is to examine the types, risk factors, and underlying mechanisms of dementia, as well as new therapy techniques, in order to maximise the chances of finding new and effective therapeutic strategies