Abstract
The Coronavirus disease 2019 (COVID-19) is caused by severe acute respiratory syndrome Coronavirus-2 (SARS CoV-2) infection attacking mainly on the immune system of a body. It is a potentially fatal disease that is of public health and economy concern globally. In December 2019, COVID-19 outbreak occurred in Wuhan city, Hubei Province, China furthermore spread worldwide. Research is underway in many countries to develop effective vaccines and drugs for the COVID-19. In Ayurveda, Acharya Charaka explained the concept of an epidemic condition in Janapadodhwans Adhayay and combating of these diseases is to be done by Panchakarma (five procedures of purification), Rasayana Chikitsa (immune-modulators therapy) and Sadvritta (good conduct). Rasayan dravyas (immuno modulators drugs) of Ayurveda can be used for health promotion, immune-modulation, prevention and reduce disease burden from COVID-19. Drugs such as Ashwagandha (Withania somnifera (L.) Dunal), Guduchi (Tinospora cordifoloia (Willd.) Miers), Amalaki (Phyllanthus emblica L.), Mulethi (Glycyrrhiza glabra L.), Shatavari (Asparagus racemosus Willd), Chireta (Andrographis paniculata (Burm.f.) Nees), Tulsi (Ocimum sanctum L.) Punarnava (Boerhaavia diffusa L.) and Pippali ((Piper longum L.) For symptom management of COVID-19 like illness Agastya Haritaki, Anutaila, AYUSH–64 can be used. Scientific research on these drugs may reveal the new approach for the prevention and management of COVID-19. The main aim of this article is to review research which has already conducted and currently being carried out on the herbal plant for their immunomodulation property which have a possible application in the prevention and treatment of COVID-19.
Highlights
From the beginning of the 21st century, three coronaviruses have caused grievous outbreaks of respiratory origin in human beings
We suggest that Ayuvedic Rasayan dravyas may be a beneficial step to combat viruses like the SARS-CoV-2 due to its antiviral and immunomodulatory properties
Concept of Epidemics and Immunomodulatory drugs in Ayurveda: An epidemic is a disease that affects a large number of populations within a community or region and the pandemic is an epidemic that's spread over multiple countries at the same time
Summary
From the beginning of the 21st century, three coronaviruses have caused grievous outbreaks of respiratory origin in human beings. Severe acute respiratory syndrome coronavirus (SARS-CoV) in 2002, Middle-East respiratory syndrome coronavirus (MERS-CoV) in 2012 and at present COVID-19 is the third coronavirus pandemic [1]. The World Health Organization (WHO) declared this disease as pandemic on 11 March 2020 [2]. In a very short period COVID-19 has caused destabilizing health systems and economy around the world. The first case of COVID-19 in India was a student who returned from Wuhan, China on January 30, 2020 [3]. On March 31, 2020, Ministry of AYUSH has issued an advisory note on a variety of immunityenhancing steps, supported by literature of Ayurveda, scientific publications and time tested approaches to resist SARS-CoV-2 infection by enhancing the immune response of the body [4].
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