Abstract
Peroxidases, widespread in the biological world, are a kind of oxidoreductases important in biological antioxidant defense systems. For great potential value of them in physiology, biochemistry and treatment of industrial pollutants, etc., they receive extraordinary attention, and also a large number of peroxidases have been found and studied on the nature and catalytic properties of them to date. Especially, horseradish peroxidase is first found and given more researches on the protein structure, catalytic mechanism and practical applications, and even modified by gene engineering and protein engineering to improve its catalytic performance. In addition, also there are numerous peroxidases that are derived from various sources or used for catalytic oxidation of different substrates, which have many differences from horseradish peroxidase in amino acid composition, active site structure, catalytic characteristics and corresponding applications. To better study and selectively employ peroxidases as biocatalysts, it is critical to comprehensively recognize various peroxidases, so as to present a reference for the in-depth and accurate studies on them in the future. In this paper, various peroxidases usually focused by enzymologists are reviewed for better mastering the completed research work on them, understanding the main interests in them, and knowing the advantages and disadvantages of them. Moreover, the research aspects that hereafter may be focused on are prospected.
Highlights
Peroxidase (POD) is an enzyme that can catalyze various biosynthesis and biodegradation reactions, which commonly requires peroxides, usually being hydrogen peroxide, as oxidant to take part in these reactions [1]
There have been some reviews on PODs to show one or more catalytic characteristics of them possibly employed in some applications
We investigated a large number of literatures, carried out a comprehensive analysis on them, and given this overview, in which a few PODs usually focused by enzymologists are reviewed for the International Journal of Bioorganic Chemistry 2020; 5(1): 10-14 purpose of fine differentiating, in-depth research and effective application on various PODs, and the future research trend of peroxidases are proposed
Summary
Tianjin Key Laboratory of Aqua-ecology and Aquaculture, College of Basic Science, Tianjin Agricultural University, Tianjin, China. To cite this article: Xin Li, Fangdi Cong, Shulin Zhang, Dajuan Zhang, Xinxin Wang. A Review on Recognition of Various Peroxidases. Received: December 5, 2019; Accepted: December 20, 2019; Published: January 8, 2020
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