A Review on Potential Anti-Inflammatory Activity of Some Medicinal Plants in Animal Model

Abstract

Inflammation is a protective response that develops against tissue injury and infection. Chronic inflammation, on the other hand, is the root cause of the pathogenesis of many inflammatory disorders, including cancer. The currently available anti-inflammatory drug therapy is often not successful or causes intolerable side effects. Therefore, the search for anti-inflammatory drugs without side effects has become a dream and ongoing effort of the Pharma companies. The concept and treatment of inflammation are described under Shotha and Shwayathu Chikitsa in Ayurveda. The concept of ama explains the pathogenesis of chronic inflammation. This review includes the anti-inflammatory activity of some medicinal plants in acute and chronic inflammatory animal models. Data were collected from existing articles on anti-inflammatory studies from various search engines. Here, a brief overview of some medicinal plants having anti-inflammatory activity along with their doses, used part extract, used animal model, and the result is provided. In this review, it was found that the majority of the selected plants have more or similar effects in comparison to standard drugs, indicating that medicinal plants have significant anti-inflammatory potential. This overview will attract the interest of investigators aiming at the design of novel therapeutic approaches for the treatment of various inflammatory conditions.