A REVIEW ON MOUTH DISSOLVING FILM

Abstract

Oral route of Mouth dissolving film is the most advanced oral solid dosage form due which it is very much in use now a day because of it’s flexibility and comfort. Mouth dissolving films are oral solid dosage form that disintegrate and dissolve within few minutes when placed in tongue without taking water. This dosage form allows the medication to bypass the first pass metabolism, so that the bioavailability of medication can be improved .Mouth dissolving film has potential to improve onset of action lower the dosing and eliminate the fear of chocking. Formulation of mouth dissolving films involves both the visual and performance characteristics as plasticized hydrocolloids, API’s taste masking agents are being laminated by solvent casting and semisolid casting method. Solvent casting method being the most preferred method over other methods because it offers great uniformity of thickness and films prepared having fine glossy look and gives them the better physical properties. Mouth dissolving films are evaluated for its various parameters like dissolution time, disintegration thickness, physical property like folding endurance. This review gives an idea about formulation techniques, evaluation parameters, overview on packaging and some available marketed products of mouth dissolving films.