Abstract

Staphylococcus aureus is among the pathogens capable of developing a broad spectrum of infections in human beings. In addition to the hospital, the bacterium is present in the community and has a high resistance to antibiotics, which is also increasing on an ongoing basis. Resistance to β-lactam antibiotic family is one of the concerns about the bacterium that has encountered the treatment of such infections with difficulty. Due to the increased resistance and importance of this bacterium, new strategies are needed to control this pathogen. One of these approaches is the use of medicinal plants, which has attracted many researchers in the last decade. Several studies have been carried out or are being designed using various herbs to find active ingredients to deal with this bacterium. The aim of this study was to present the antibacterial activity of different medicinal plants and the effects of their active ingredients on methicillin-resistant and methicillin-sensitive S. aureus and to clarify the pathway to further studies in this regard.

Highlights

  • Staphylococcus aureus is a gram-positive bacterium colonized on the skin, and present in the nose of 25% to 30% of healthy people [1]

  • Four fractions were obtained and the fraction 3 had an inhibitory effect on the strains studied, which showed the zone of inhibition (ZOI) diameter of 15.09, 13.25, 14.12 mm, and the minimum inhibitory concentration (MIC) values of 88.16, 128.11 and 116.12 μg/mL, respectively [56]

  • During a research on Gynoxys verrucosa Wedd, which is one of the traditional southern Ecuadorian herbs, the results showed that the extract of this plant had a poor antibacterial activity

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Summary

Journal of Herbmed Pharmacology

A review on medicinal plant extracts and their active ingredients against methicillin-resistant and methicillinsensitive Staphylococcus aureus.

Introduction
Staphylococcus aureus MRSA
Methanol extract Aqueous crude extract
Findings
Conclusion
Full Text
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