Abstract
An effective wound dressing material should be flexible structure, biocompatible, maintain wound moisture and adsorb exudate. The rate of the wound healing process depends on the type of wound care dressing materials. The chitosan-based dressing has become attention for wound dressing application for decades. This study aims to review the mechanical characterization of chitosan-based material for wound healing applications. In this review, the process of searching research papers was performed according to the PRISMA-P protocol that begins by searching literature on the selected databases such as Science Direct, PubMed, and Google Scholar from the year of 2012 to 2022. The pre-determined keywords (chitosan-based material, physicochemical characterization, wound dressing, wound healing, wound treatment) were used in data searching protocol. The search retrieved 284 articles. Assessment of eligibility retrieved 19 articles based on the inclusion and exclusion criteria. This review provides the knowledge of physicochemical characterization studied on chitosan-based wound dressing material including the porosity, swelling behaviour, water vapour transmission rate and mechanical properties.
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