A REVIEW ON MANAGEMENT PRINCIPLES AND MEDICATION OF MYOCARDIAL INFARCTION

Samridhi Khandelwal Samridhi Khandelwal,Dinesh Sharma Dinesh Sharma,Vandana Sharma Vandana Sharma,Shailendra Tripathi Shailendra Tripathi,Gopal Kumar Paswan Gopal Kumar Paswan,Bhairvi Kumari Bhairvi Kumari

doi:10.32553/jbpr.v9i4.773

Samridhi Khandelwal Samridhi Khandelwal, Dinesh Sharma Dinesh Sharma + Show 4 more

Open Access

https://doi.org/10.32553/jbpr.v9i4.773

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Abstract

Myocardial infarction is the most common public health issue and a major cause of death including disorders of heart and blood vessels. Among all heart problems, ventricular fibrillation is the major cause that occurs soon after the onset of ischemia. As the patient reaches hospital major aim is to decrease the size of the infarct. The control and management of MI depend on the pathophysiological conditions and the time course of irreversible myocardial injury. The fundamental goals of managing acute MI include: (i) Duration of exposure of myocardium to ischemia should be minimized. (ii) Rapid reperfusion (iii) Preventing recurrent ischemia and re-occlusion. (iv) Managing cardiac arrhythmia and other mechanical complications. Management of MI requires prompt diagnosis and therapy including Fibrinolytic therapy, Antithrombin agents, Antihypertensive, and currently discovered many kinds of drugs including LCZ696 and new FDA- Approved treatment and therapies.

Highlights

Myocardial infarction is a medical emergency and the most common cause of death
Acute myocardial infarction usually results from an imbalance in oxygen supply and demand which is most often caused by complete occlusion of a coronary artery with atherosclerotic plaque
Resuscitation success is critically time dependent as after each minute of ventricular fibrillation survival reduces 7% to 10%.Epidemiological studies reveals that 60% to 73% of deaths associated with ST elevation occurs out of hospital within [1,2] hrs after attack leads to early death as a result of cardiac arrest caused by ventricular fibrillation

Summary

Introduction

Myocardial infarction is a medical emergency and the most common cause of death. Patients in which ventricular fibrillation develops, the majority of them die before they obtain medical attention. Due to this in order to reduce deaths, it is important to take measures to educate common people about symptoms and signs of acute myocardial infarction so that patients can get CPR and local management as soon as possible.

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