Abstract
Label-free biosensing has advanced significantly in recent years due to its capacity for quick and inexpensive bio-detection in small volumes. Additionally, they have developed into lab-on-a-chip technology and may be able to perform real-time analysis. In this regard, we have talked about label-free bio sensing based on a range of transducers, operational concepts, novel nanomaterial, device fabrication, and application. Recent developments in label-free biosensor technology, including aptamer-based sensors, field-effect transistor-based biosensors, optical-based biosensors, SPR, LSPR-based biosensors, and paper biosensors based on nanobiotechnology, are highlighted. It is intended to give the reader a reason to peep into the planet of label-free biosensors.
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