Abstract
Many phytochemicals such as tannins, terpenoids and flavonoids are hydrophilic in nature, but have low absorption, because they are unable to cross lipid membranes of cells. It has been proposed to combine phytomedicine to nanotechnology, because nanocarrier can deliver active phytochemical during entire treatment period, directing it to the desired site of action. The main aim of this work is to review Phytochemicals which possess promising anti-carcinogenic capabilities in a variety of skin cancer cell lines, animal models and their mechanism of action. The commercial formulations for skin cancer prevention and therapy that are now on the market that is derived from plants are also covered in this review. This paper focused on the recent assessment of the biological obstacles to topical applications of phytoconstituents and also focuses on review of the enormous potential for bioactive phytochemical distribution via developing nanotechnology.
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