A review on chemical and pharmacological interest of morpholine and pyrans derivatives

Abstract

Morpholine is a six-membered aromatic organic heterocycle that possesses one nitrogen atom and one oxygen atom their ring structure. Morpholine ring is present in various organic compounds those were developed by chemical designing for diverse pharmacologically activities. In recent years, scientists have explored this moiety. This review summarizes the broad spectrum of pharmacological profile of morpholine derivatives. Six-membered heterocyclic compounds containing oxygen like 2H-pyran and 4H-pyrans constitute an important class of biologically active compounds, playing an essential role in biochemistry and continuing to attract interest. Pyrans and its analogues engage prime position due to their diverse applications. In this review, up to date information about the developments and exploration of methodologies of morpholine and pyran analogues were discussed. This review shows current tendency in the morpholine and pyran analogues and reveals their potent pharmacophoric activities. This article will support to the researcher in future to design and synthesized novel morpholine and pyran derivatives.