Abstract

Background: Saireyaka (Barleria prionitis Linn.) of is one of the most useful plant in Ayurveda. Many pharmacological studies have been conducted to investigate the properties of Saireyaka (Barleria prionitis Linn.) in an attempt to authenticate its use as a multi-purpose medicinal agent. The objective of this paper is to review the literature regarding Saireyaka (Barleria prionitis Linn.) Specifically, the literature was reviewed for articles pertaining to chemical properties and therapeutic benefits. This review is in a narrative format and consists of all publications relevant to Saireyaka (Barleria prionitis Linn.) that were identified by the authors through a Google scholar search and books from Central library and library of Dravyaguna Vigyan department of Sai Ayurved College, Hospital and Research Centre Sasure-Vairag-Solapur. Result shows that Saireyaka (Barleria prionitis Linn.) possesses antimicrobial, antiviral, hepatoprotective, antioxidant, anticancer, anti-inflammatory, thrombolytic and diuretic properties. The mechanisms of action for these properties are not fully understood. Preliminary studies have found various constituents of Saireyaka (Barleria prionitis Linn.) exhibiting a variety of therapeutic effects. These results are very encouraging and indicate this herb should be studied more extensively to confirm these results and reveal other potential therapeutic effects. Saireyaka (Barleria prionitis Linn.)is an Ayurvedic medicinal plant which is mentioned in Ayurvedic classical books.it is one of the plant which According to Ayurveda this plant is having Ras-Katu, Veerya-Ushna, Vipaka-Katu, Vaatahar and Kaphahar and Sheet . Many pharmacological studies have been conducted to investigate the properties of Saireyaka (Barleria prionitis Linn.) in an attempt to authenticate its use as a multi-purpose medicinal agent. The main aim of this article is to collect and analyze the scientific information related to traditional uses, bioactive chemical constituents and pharmacological activities. Methods: Scientific information on Saireyaka (Barleria prionitis Linn.) was retrieved from the online bibliographic databases (e.g. MEDLINE/PubMed, SciFinder, Web of Science, Google Scholar and Scopus) and books from central library as well as library of Dravyaguna department of Sai Ayurved College, Hospital and Research Centre Sasure-Vairag-Solapur. Results: Different plant parts of Saireyaka (Barleria prionitis Linn.) were reported to be used for the treatment of natural hair color, cough, skin diseases, and antidote in various poisonous bites such as rat bite. Various extracts were evaluated for their antibacterial, anti-inflammatory, antimicrobial, antidiabetic, hypolipidimic, antioxidant, thrombolytic property, hepatoprotective activity . Conclusion: The mechanisms of action Saireyaka (Barleria prionitis Linn.) for these properties are not fully understood. Preliminary studies have found various constituents of exhibiting a variety of therapeutic effects. These results are very encouraging and indicate this herb should be studied more extensively to confirm these results and reveal other potential therapeutic effects.

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