A Review on Angiosarcoma of the Breast: Case Studies

Abstract

An uncommon kind of cancer called angiosarcoma originates in the lining of lymph and blood arteries. The immune system includes the lymphatic vessels. The lymph vessels remove waste materials, viruses, and germs from the body. Any region of the body can develop cancer of this kind. Angiosarcoma is an aggressive tumour, It is a form of soft tissue sarcoma. The treatment of angiosarcoma is very difficult. Breast cancer arises in the breast's lymphatic or blood vessel networks eventually migrating to the breast and the skin of the arms. Most angiosarcomas have unknown origins. Researchers have found a number of variables that could raise the disease's risk. Angiosarcoma develops when the DNA of cells lining a blood artery or lymph channel changes. The instructions that inform a cell what to do are encoded in its DNA. The adjustment which scientists refer to as mutations, instruct the cells to divide quickly. When healthy cells would perish, the alterations prevent the cells from dying. As a result, cancer cells can accumulate and spread outside of the blood vessel or lymph channel. Cancerous cells are able to infiltrate and obliterate healthy body tissue. Cancer cells could eventually separate and travel to different parts of the body. Angiosarcomas have a rapid development rate and body-wide dissemination. Breast angiosarcomas come in two varieties, primary and secondary, and they are both treated surgically by removing the tumour. Angiosarcoma can be spread in other part of body from breast. Primary breast angiosarcoma is an uncommon kind of breast cancer that only affects women, typically developing in the third to fourth decade. For diagnosis, biopsy, mammogram, breast MRI, PET Scan, ultrasound were performed and for the treatment of breast cancer surgery, chemotherapy, radiotherapy were performed. Only 0.04% of malignant breast tumours are primary breast angiosarcomas, making it a rare form of breast cancer. Secondary malignant tumour growth is one of the dangers of therapeutic radiation. In this paper, various cases are reported of angiosarcoma of the breast.