Abstract

Eriobotrya japonica Lindl., named as loquat, is a subtropical fruit tree of the family Rosaceae which is well known medical plant originated in Japan and China. Loquat portions, like leaves, peels and fruits have been shown to possess various health usefulnesses. In Chinese classical medicine, it is vastly utilized in many illnesses, like gastroenteric disorders, diabetes mellitus, pulmonary inflammatory diseases and chronic bronchitis. Loquat plant contain many active constituents, such as flavonoids, carotenoids, vitamins, polyphenolic compounds, other that have many biological effects like anti-tumor, anti-diabetic, anti-inflammatory, anti-mutagenic, antioxidant, antiviral, antitussive, hepatoprotective and hypolipidemic activity.

Highlights

  • The genus Eriobotrya, distributed in subtropical and tropical Southern and Eastern Asia, comprises about 26 species [1].Loquat is implanted mostly to fruit production and in the Chinese classical medicine; its leaf has been utilized [5].Eriobotrya japonica (Thunb.) Lindl. is a green fruit tree of medium sized belong to family Rosaceae

  • The total triterpenes decreased the inflammatory cytokines production by suppressing NF-κB stimulation from alveolar macrophages in chronic bronchitis rat model [50]. The another model that is utilized to estimate the anti-inflammatory property of Eriobotrya japonica extract is a mouse paws edema model [51,52] In the mouse macrophage-like RAW 264.7 cells, loquat tea water extract shown inhibitory effects on the expression of tumor necrosis factor-α (TNF-α), interleukin-6, nitric synthase, and nitric oxide (NO) through the downregulation of pathways of the TGF-β-activated kinase-mediated NF-κB and MAPK [51]

  • Rashed et al (2014) reported that methanol extract (80%) of stems of loquat was demonstrated antimicrobial effect versus strains of fungi and bacteria related to the presence of triterpenes and flavonoids

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Summary

Introduction

The genus Eriobotrya, distributed in subtropical and tropical Southern and Eastern Asia, comprises about 26 species [1]. Loquat is implanted mostly to fruit production and in the Chinese classical medicine; its leaf has been utilized [5]. Is a green fruit tree of medium sized belong to family Rosaceae. The local English name of the plant (loquat); Arabic (Beshmelah); German (Loquate); French (bibassier); Chinese (luju,biba), etc.It attains up to 6 meters or more height, with thick and evergreen oval-oblong leaves. Loquat has been utilized in the jam, chutney and jelly preparation, in addition to it is eaten as a fresh fruit [4]

Iraqi Journal of Pharmaceutical Science
Cytotoxic activity
Conclusions
Findings
Hepatoprotective Effect of Eriobotrya japonica
Full Text
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