Abstract

T-2 toxin is a secondary fungal metabolite that belongs to the trichothecene mycotoxin family. T-2 toxin can lead to the structural and functional changes of cartilage cells and cartilage cell degeneration and necrosis. With strong cytotoxicity, T-2 toxin can cause definite damage to cartilage cells. In this paper, we reviewed recent studies on the effects of T-2 toxin on chondrocyte apoptosis, ultra structural changes and extracellular matrix in vitro. Key words: T-2 toxin; Chondrocytes; In vitro

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