Abstract

Sepsis-induced cardiomyopathy is a reversible myocardial dysfunction that typically resolves in 7–10 days. It is characterized by left ventricular dilatation and depressed ejection fraction. However, many uncertainties exist regarding the mechanisms, characteristics, and treatments of this condition. Therefore, this review attempts to summarize our current knowledge of sepsis-induced cardiomyopathy.

Highlights

  • Sepsis is a dysregulated systemic inflammation caused by infections involving various organs

  • Sepsis-induced cardiomyopathy is a complication of severe sepsis and septic shock first described by Parker et al in 1984 as a reversible myocardial depression that occurs in patients with septic shock [1]

  • The number of patients is less, these results suggest that decreased ejection fraction may be caused by ventricular dilatation and not by decreased stroke volume

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Summary

Introduction

Sepsis is a dysregulated systemic inflammation caused by infections involving various organs. Sepsis-induced cardiomyopathy has three characteristics: left ventricular dilatation, depressed ejection fraction, and recovery in 7–10 days. Characteristics of sepsis-induced cardiomyopathy In 1984, Parker et al reported decreased ejection fraction and increased end-diastolic volume in septic shock survivors.

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