Abstract

To date, the Her-2 receptor is the most frequently detected breast cancer biomarker which can be monitored on the surface of tumors by proton magnetic resonance imaging (1H MRI). In the past decade, we observed major advances in the development of 1H MRI as a diagnostic tool in cancer studies. 1H MRI is noninvasive method and can be used to explore tumor biology, cancer cell surface morphology and provide information about drug efficacy, absorption, distribution, and elimination. This review describes current studies of Her-2 targeting with trastuzumab and the application of 1H MRI to Her-2 receptor detection.

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