A review of lignin application in hydrogel dressing

Abstract

Lignin is the most abundant natural aromatic polymer in the world. Currently, researchers have developed a number of lignin-based composite materials that are widely used in various fields, including industry, agriculture and medicine. Especially in recent years, lignin has attracted great interest as a high-value product for biomedical applications. Due to its antioxidant, antibacterial, adhesive and other properties, lignin is a promising candidate for the development of hydrogel dressings. However, there is no comprehensive overview of the application of lignin-based hydrogel dressings. In this review, lignin-based hydrogel skin dressings were first presented, and the preparation methods of physical and chemical crosslinking in lignin-based hydrogel dressings were discussed. In addition, various functional and environmentally responsive lignin-based hydrogel dressings were primarily reviewed. Finally, the prospects for the development of novel multifunctional lignin-based hydrogel dressings in the future were presented. In conclusion, this review provided a timely and comprehensive summary of the latest advances in the use of lignin as a biomaterial for hydrogel dressings, which would provide valuable guidance for the further development of lignin-based hydrogels.