A review of current phase III clinical trials of plaque psoriasis: under-representation of nonwhite participants and need for reform.

Abstract

Plaque psoriasis is a chronic inflammatory skin condition that affects an estimated 0.91% to 8.5% of the global population.1 The prevalence of psoriasis varies based on ethnoracial and geographic distribution. In the United States, psoriasis affects approximately 3.6% of Caucasians (non-Hispanic white), 1.9% of African Americans (non-Hispanic black), and 1.6% of Hispanic-identifying adults.2 Population-based studies in East and Southeast Asia have estimated a prevalence ranging from 0.05 to 0.47%.3.