A Review of COVID19 associated factors: CRP, Creatinine, Bilirubin, VLDL, HDL, Triglycerides, Cortisol and Thyroid Function

Abstract

The objective was to identify key factors associated with compromised immunity in search of preventative solutions that can safeguard health. Elevated C-reactive protein (CRP) synthesized by cytokines, creatinine, and bilirubin are consistently featured in the profiles of COVID-19 patients, indicating persistent inflammation, oxidative stress and excess toxicity. Accumulated adiposity, BMI>25, and abnormalities in VLDL, cortisol, triglycerides, and thyroid function have been mostly indirectly linked to COVID-19 by their conspicuous presence in obesity, diabetes, pulmonary defects, and cardiovascular diseases that exacerbate COVID-19 vulnerability and fatality rates. The COVID-19 documented affinity for ACE2 receptors which are primarily expressed in adipose tissue, heart, thyroid, and male tissues, unveils the virus’ principal targets, and emphasizes the importance of striving for cardiovascular health, weight control, and metabolic stability. Exercise is universally accepted as an optimal solution, however, the expense, length of commitment, and effort involved in sustained physical activity become progressively more challenging with hormonal disharmony, and an imbalanced lipid profile, consequently multiplying the incidences of obesity. We explored the effects of an exercise alternative that demonstrated reduced visceral adiposity, lower levels of CRP, creatinine, bilirubin, cortisol, VLDL, and triglycerides, juxtaposed by upraises in HDL and Free T3. Importantly, all variables optimally increased and decreased without ever drifting into abnormality.