Abstract
Background Solid pseudopapillary tumor of the pancreas (SPTP) has been reported as a rare disease with low malignant potential. The aim of this study was to summarize experiences of the diagnosis and treatment for the patients reported in the Chinese population. Method 2450 SPTP cases reported in English and Chinese literature before Jan 2020 were for our review and analysis retrospectively. Result There are 389 male cases and 2061 female cases, and the ratio of male/female was 1 : 5.3. The average age was 29.3 years. The main clinical symptoms were upper abdominal pain and bloating discomfort in 51.6% of the cases and epigastric mass. 38.6% of the tumor was located at the head of the pancreas and 55.4% at the body and tail of the pancreas. The most frequent operative styles were tumor enucleation (38.4%). Pathology showed that the average diameter of the tumor was 8.2 cm and 12.3% of SPTP was malignant. 98.3% of cases had favorable survival. Conclusions SPTP is a rare indolent tumor occurring mainly in young women, and the main clinical performances are abdominal mass and abdominal pain; most tumors are distributed at the head and the tail of the pancreas; the prognosis after complete resection is excellent.
Highlights
Solid pseudopapillary tumor of the pancreas (SPTP) has been reported as a rare disease with low malignant potential
Due to the Chinese population of a large sample, the aim of this study is to execute the systematic review of all the available researches of SPTP published in the English and Chinese literature for summarizing clinicopathological and therapeutic experiences in the Chinese population
SPTP-related literatures covered in PubMed, Web of Science, SinoMed database, Wanfang Data Corp., and China National Knowledge Infrastructure (CNKI) before Jan. 2020 were retrieved
Summary
Solid pseudopapillary tumor of the pancreas (SPTP) has been reported as a rare disease with low malignant potential. 2450 SPTP cases reported in English and Chinese literature before Jan 2020 were for our review and analysis retrospectively. SPTP is a rare indolent tumor occurring mainly in young women, and the main clinical performances are abdominal mass and abdominal pain; most tumors are distributed at the head and the tail of the pancreas; the prognosis after complete resection is excellent. Before 2010, most articles focused on the case reports or case series involving fewer than 20 patients. After 2010, most articles concentrated on the observational study of large-scale case series of more than 50 patients. A total of 390 cases [6] and 553 cases [7] were reviewed in the SPTP reported in Chinese literature. A nationwide survey from China [8] and South Korea [9] revealed that SPTP ranked as the first (31.7%) and the third (18.3%) common in the pancreatic cystic tumors (18.3%)
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