Abstract
To describe brucellosis infectious as a zoonotic disease, which is caused by Brucella spp. Brucellosis is considered to be a major health and economic challenge in developing countries, including Iran. This study focuses on epidemiology human's and animal's brucellosis and disease control strategies. Test-and-slaughter technique and extensive livestock vaccination programs are used for eradication of brucellosis. Test-and-slaughter is a general policy in Middle Eastern countries to eradicate the disease. Under this program, the Rose Bengal plate test is used as a screening measure to identify the infected herd, whereas the complement fixation test is applied as a confirmatory test. The prevalence of bovine brucellosis in 2015–2016 ranged between 7.2 and 18.1% in Kuwait and Jordan and ranged between 3 and 3.1% in Iraq and Iran in 2012–2014. Prevalence of goat brucellosis (Brucella melitensis) was 3.5% in Iran in 2014. Test-and-slaughter is used in most of the countries where the prevalence rate of the disease does not exceed 2%. Since 1963, testing the vaccine efficacy in goats and sheep has proven that vaccination can decrease the epidemic rate of the disease from 45 to 1.8%. This study indicated the test-and-slaughter technique alone has not proven successful in the eradication of brucellosis in Iran, and animal vaccination is essential to the control and eradication of animal and human brucellosis.
Published Version
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