A Review: In Silico Study and Characterization Bioactive Compound by using LCMS Techniques from Plant Extract

Abstract

An in silico study is one performed via simulation on a computer. In silico simulations are frequently used to predict how a compound will react with proteins in the body or with pathogens. Bacterial sequencing techniques represent a group of in silico methods that are used to identify bacteria. These techniques sequence bacterial DNA and RNA. Polymerase chain reaction (PCR) is the most commonly used technique, a method that has become more widely known due to its use in testing for COVID-19. Another popular in silico method of molecular modeling, a technique capable of showing how therapeutic molecules interact with the nuclear receptors of cells. Natural products, such as plants extract, either as pure compounds or as standardized extracts, provide unlimited opportunities for new drug discoveries because of the unmatched availability of chemical diversity. According to the World Health Organization (WHO), nearly 20,000 medicinal plants exist in 91 countries including 12 mega biodiversity countries.