Abstract
The native horse heart ferricytochrome c molecule is less compact than ferrocytochrome c and more readily undergoes alcohol induced disruption of the heme crevice. Carboxymethylation of methionine 80 of cytochrome c reverses the relative strengths of the heme crevice and the susceptibility to alcohol induced conformational changes. An explanation for this dramatic change is suggested.
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Schedule a callMore From: Biochemical and biophysical research communications
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