A reusable and heterogeneous Ti(IV) anchored MCM-41 catalyzed hydroacylation and hydroamination reactions

Abstract

An efficient, mild and reusable catalytic hydroacylation and hydroamination reactions have been developed by using heterogeneous Ti(IV) anchored MCM-41 catalyst from various aryl, heteroaryl, aliphatic aldehydes as well as aryl and aliphatic amines with dialkyl azodicarboxylate. The catalyst gives excellent yields of desired products, a wide range of substrate scope in hydroacylation and hydroamination and para-selectivity is observed with unprotected amines. The catalyst (Ti-MCM-41) was prepared by a modified strategy and reused more than five catalytic cycles without any significant yield loss in these reactions.