Abstract

Diagnosis: Papular-purpuric gloves-and-socks syndrome secondary to parvovirus B19 infection. Given the persistent fever, hematologic abnormalities, and new rash, a diagnostic workup for viral illness was performed. Viral serologic tests were performed, including tests for hepatitis B virus, hepatitis C virus, Epstein-Barr virus, cytomegalovirus, and parvovirus B 19. Results of tests for hepatitis B virus surface antigen, hepatitis C virus antibody, and IgM against EpsteinBarr virus viral capsid antigen were negative, as was the result of a mononucleosis spot test. The serologic titer for parvovirus B19 IgG was 5.03 (>1.10 is defined as a positive result), and the titer for parvovirus B19 IgM was 6.79 (>1.10 is a positive result). Serum tested positive for parvovirus B19 by PCR. The patient remained febrile but better tolerated intake of food and liquids. Therefore, the patient was discharged to home. At a follow-up examination 1 week later, he was afebrile and had no rash or lymphadenopathy, and laboratory values were normal.

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