A Retrospective Study to Evaluate the Role of Dynamic Fracture Mobility in the Conservative Treatment of Osteoporotic Vertebral Compression Fractures

Abstract

To investigate whether dynamic fracture mobility could affect the outcome of conservative treatment in patients suffering from acute osteoporotic vertebral compression fracture (OVCF). A total of 158 patients who underwent conservative treatment in our hospital for painful OVCFs were included in this study and their data were retrospectively analyzed. According to the degree of pain relief, patients were divided into excellent efficacy group and poor efficacy group. Factors that may affect the outcome of conservative treatment were recorded for each patient. Variables with a statistical difference between two groups were entered into multivariate logistic regression analysis to identify the factors influencing the outcome of conservative treatment. Receiver operator characteristics curve (ROC) analysis was also performed. The result demonstrated dynamic fracture mobility, overweight, age and BMD (all P < 0.001) were independent factors influencing the outcome of conservative treatment. ROC analysis revealed that the cut-off values for age and BMD that predicted treatment effect were 72.5 years old and -3.30, respectively. This study confirmed that dynamic fracture mobility could be used as an independent factor predicting the outcome of conservative treatment in patients suffering from acute OVCFs. It was also demonstrated that overweight, age and BMD were other independent factors influencing the outcome of conservative treatment. A comprehensive evaluation of these related factors can guide the doctor to take appropriate treatment for a unique acute OCVF.