A retrospective study of clinical profile of para-phenylenediamene poisoning (hair dye poisoning) in cases admitted in medical college

Abstract

India has a high suicide rate and a large proportion of these suicides occur through poisoning. Poisoning by Hair dye has been increasing and constitutes a large proportion of the poisoning cases. The principle toxic constituent of Hair dye poisoning is Paraphenylenediamine (PPD).Present study was done by analyzing the demographic profile, clinical presentation, biochemical profile, life saving interventions and mortality in cases of PPD poisoning. This study was conducted on 80 cases. Angioedema, pain in oral cavity, dark coloured urine, oro-facial edema were main clinical features. Raised TLC count, elevated liver enzymes (sgpt, sgot), elevated serum creatinine, hypocalcemia, elevated bilirubin, low haemoglobin.Paraphenylene diamine poisoning is developing now days due to easy obtainability and low cheap price. It is more common in poor, illiterate, married females of younger age group living in rural areas. Aggressive treatment and Tracheostomy can save life of Patients.