A retrospective review of 61 cases of adenomatoid odontogenic tumour seen in five tertiary health facilities in Nigeria.

Olufemi Gbenga Omitola,Olujide Oladele Soyele,Akinyele Olumuyiwa Adisa,Benjamin Fomete,Ahmed Oluwatoyin Lawal,Olajumoke Ajibola Effiom,Adetokunbo Olawuyi

doi:10.11604/pamj.2016.24.102.9400

Abstract

IntroductionAdenomatoid odontogenic tumor (AOT) is a benign lesion originating from the dental lamina or its remnants. It is a relatively uncommon neoplasm representing about 3% of all odontogenic tumors. The aim of this study was to examine the clinical and radiological characteristics of AOTs in five major tertiary centres in Nigeria.MethodsArchival hospital-based data stores of five tertiary health facilities in Nigeria were accessed. Case files and biopsy records were retrieved to obtain relevant information. Data was collected according to a proforma for standardization and entered into and analysed using SPSS for Windows (version 20.0; SPSS Inc. Chicago, IL).Results61 (4.5%) cases of AOT were documented. The age range was 8-46 years with a mean age of 20.4±9.9 years. Male: Female ratio was 1:1.3. The anterior maxilla had 34 (55.8%) cases and the anterior mandible had 20 (32.8%) cases. 40 (65.6%) follicular cases, 20 (32.8%) extra-follicular cases and 1(1.6%) extra-osseous case were found. 31 cases (61.1%) were associated with impacted teeth and the upper canine was involved in 19 (57.6%) cases.ConclusionThis study showed AOT to be more common in the maxilla, more in females, most often associated with impacted canines, however, the suggestion of AOT being a “Two third tumour” was not observed in this study.

Highlights

Adenomatoid odontogenic tumor (AOT) is a benign lesion originating from the dental lamina or its remnants
This study generally observed the clinical trend of AOT being more common in the maxilla, more prevalent in females, most often associated with impacted canines and presenting mostly as the follicular clinico-topographic variant
We suggest that more extra-follicular AOTs seen in this study could account for a relative higher percentage of mandibular presentation and a relatively higher mean age compared with previous studies

Summary

Introduction

Adenomatoid odontogenic tumor (AOT) is a benign lesion originating from the dental lamina or its remnants [1] It is a relatively uncommon neoplasm representing about 3% of all odontogenic tumors and was first described by Steensland in 1905 [2, 3]. AOT was previously described as; adenoameloblastoma, ameloblastic adenomatoid tumor, adamantinoma, epithelioma adamantinum or teratomatous odontoma [4] It was Philipsen and Birn who first introduced the term “AOT” in 1969 and this was later adopted by WHO in her first histological typing of odontogenic tumors, jaw cysts and allied lesions in 1971 [1,5]. The tumor is sometimes described as the “two third tumour”, since, two third of cases occur in the maxilla, two third affects young females, two third is associated with an un-erupted tooth and two third of affected teeth are canines [8, 9].

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