Abstract

Psychiatric disorders are now widely recognized as a major contributor to the global burden of disease. It has been described that there is an increased risk of adverse effects when more than one psychotropic drug is prescribed. Knowledge of the pattern of utilization of drugs in the general population can be achieved through the conduct of drug utilization studies. The present study has therefore been conducted to observe the pattern of drug use in psychiatry patients in a tertiary care hospital.
 Aim and Objective:
 To assess the epidemiology of various psychiatric illnesses among the study population
 To assess the Prescribing Pattern of drugs in Psychiatric Illness.
 To assess the drug-drug interactions in the prescription using MICROMEDEX.
 Methodology: A retrospective descriptive observational study was performed in a tertiary care hospital. A total of 100 prescriptions were collected from MRD. 
 Results: The study reported that 66% of patients were males and 34% were females. The average number of drugs and psychotropic drugs per prescription is six and four respectively. Around 61.98% of drugs in the prescription are psychotropic drugs, among that 40.17% of benzodiazepines are majorly used, followed by 34.27% of antipsychotics. Almost 95 prescriptions had a minimum of one drug-drug interaction. 
 The average number of psychotropics per prescription was higher than in studies. The average number of drugs per prescription was 5.84, which lead to polypharmacy.
 Conclusion: Using WHO indicators prescription analysis was done and it showed some deviation from the standard value which can be improved. Polypharmacy was noted in this study. Most of the drug is prescribed in the brand name which should be avoided.

Highlights

  • Psychiatric disorders are widely recognized as a major contributor to the global burden of disease

  • It has been reported that there is an increased risk of adverse effects in psychotropic polypharmacy compared to monotherapy [2,6] High dose treatment is caused by antipsychotic Polypharmacy; In the treatment of the mental and behavioral disorders, EPS occurs as an important risk because they may impair quality of life, be annoying and lead to poor adherence

  • A total of 100 prescriptions were analyzed, demographic data revealed that 66% of patients with psychiatric illness were male and 34% were females

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Summary

Introduction

Psychiatric disorders are widely recognized as a major contributor to the global burden of disease. In the treatment of most mental and behavioral disorders, psychotropic drugs like anxiolytics, hypnotics, antidepressants, and antipsychotics play an important and major role [1]. It has been reported that there is an increased risk of adverse effects in psychotropic polypharmacy compared to monotherapy [2,6] High dose treatment is caused by antipsychotic Polypharmacy; In the treatment of the mental and behavioral disorders, EPS occurs as an important risk because they may impair quality of life, be annoying and lead to poor adherence. The risk of EPS induced by antipsychotics is reported to increase dose-dependently. Certain guidelines recommend monotherapy as the basis for the treatment and indicate that combination therapy should be considered only after some monotherapies have failed [9,8] Knowledge of the pattern of utilization of drugs in the general population can be achieved through the conduct of drug utilization studies. The present study has been conducted to observe the pattern of drug use in psychiatry patients in a tertiary care hospital

Methods
Results
Conclusion

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